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Pathway enrichment analysis (PEA) suggests ivs+ CD8 + T cells have an enhanced ability to interact with endothelial cells (A) Tree plot illustrating significantly enriched pathways in lung ivs+ CD8 + T cells. Hierarchical clustering of enriched terms based on Jaccard’s similarity index (JC). (B and C) Gene-concept network plots depicting genes (blue dots) involved in enriched terms (red dots) associated with signaling events (B) and vascular interactions (C). (D) <t>Reactome</t> “cell surface interactions at the vascular cell wall” pathway associated genes upregulated or downregulated in lung ivs+ CD8 + T cells. For PEA an adj p value (FDR) ≤ 0.05 was used to determine significance. See also and .
Reactome Gene Collection, supplied by Broad Institute Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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reactome  (Qlucore Inc)
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Pathway enrichment analysis (PEA) suggests ivs+ CD8 + T cells have an enhanced ability to interact with endothelial cells (A) Tree plot illustrating significantly enriched pathways in lung ivs+ CD8 + T cells. Hierarchical clustering of enriched terms based on Jaccard’s similarity index (JC). (B and C) Gene-concept network plots depicting genes (blue dots) involved in enriched terms (red dots) associated with signaling events (B) and vascular interactions (C). (D) <t>Reactome</t> “cell surface interactions at the vascular cell wall” pathway associated genes upregulated or downregulated in lung ivs+ CD8 + T cells. For PEA an adj p value (FDR) ≤ 0.05 was used to determine significance. See also and .
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Pathway enrichment analysis (PEA) suggests ivs+ CD8 + T cells have an enhanced ability to interact with endothelial cells (A) Tree plot illustrating significantly enriched pathways in lung ivs+ CD8 + T cells. Hierarchical clustering of enriched terms based on Jaccard’s similarity index (JC). (B and C) Gene-concept network plots depicting genes (blue dots) involved in enriched terms (red dots) associated with signaling events (B) and vascular interactions (C). (D) <t>Reactome</t> “cell surface interactions at the vascular cell wall” pathway associated genes upregulated or downregulated in lung ivs+ CD8 + T cells. For PEA an adj p value (FDR) ≤ 0.05 was used to determine significance. See also and .
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Pathway enrichment analysis (PEA) suggests ivs+ CD8 + T cells have an enhanced ability to interact with endothelial cells (A) Tree plot illustrating significantly enriched pathways in lung ivs+ CD8 + T cells. Hierarchical clustering of enriched terms based on Jaccard’s similarity index (JC). (B and C) Gene-concept network plots depicting genes (blue dots) involved in enriched terms (red dots) associated with signaling events (B) and vascular interactions (C). (D) <t>Reactome</t> “cell surface interactions at the vascular cell wall” pathway associated genes upregulated or downregulated in lung ivs+ CD8 + T cells. For PEA an adj p value (FDR) ≤ 0.05 was used to determine significance. See also and .
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Pathway enrichment analysis (PEA) suggests ivs+ CD8 + T cells have an enhanced ability to interact with endothelial cells (A) Tree plot illustrating significantly enriched pathways in lung ivs+ CD8 + T cells. Hierarchical clustering of enriched terms based on Jaccard’s similarity index (JC). (B and C) Gene-concept network plots depicting genes (blue dots) involved in enriched terms (red dots) associated with signaling events (B) and vascular interactions (C). (D) <t>Reactome</t> “cell surface interactions at the vascular cell wall” pathway associated genes upregulated or downregulated in lung ivs+ CD8 + T cells. For PEA an adj p value (FDR) ≤ 0.05 was used to determine significance. See also and .
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reactome pathway analysis with voronoi visualization  (Broad Institute Inc)
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Pathway enrichment analysis (PEA) suggests ivs+ CD8 + T cells have an enhanced ability to interact with endothelial cells (A) Tree plot illustrating significantly enriched pathways in lung ivs+ CD8 + T cells. Hierarchical clustering of enriched terms based on Jaccard’s similarity index (JC). (B and C) Gene-concept network plots depicting genes (blue dots) involved in enriched terms (red dots) associated with signaling events (B) and vascular interactions (C). (D) <t>Reactome</t> “cell surface interactions at the vascular cell wall” pathway associated genes upregulated or downregulated in lung ivs+ CD8 + T cells. For PEA an adj p value (FDR) ≤ 0.05 was used to determine significance. See also and .
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reactome  (Novogene)
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Pathway enrichment analysis (PEA) suggests ivs+ CD8 + T cells have an enhanced ability to interact with endothelial cells (A) Tree plot illustrating significantly enriched pathways in lung ivs+ CD8 + T cells. Hierarchical clustering of enriched terms based on Jaccard’s similarity index (JC). (B and C) Gene-concept network plots depicting genes (blue dots) involved in enriched terms (red dots) associated with signaling events (B) and vascular interactions (C). (D) <t>Reactome</t> “cell surface interactions at the vascular cell wall” pathway associated genes upregulated or downregulated in lung ivs+ CD8 + T cells. For PEA an adj p value (FDR) ≤ 0.05 was used to determine significance. See also and .
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Pathway enrichment analysis (PEA) suggests ivs+ CD8 + T cells have an enhanced ability to interact with endothelial cells (A) Tree plot illustrating significantly enriched pathways in lung ivs+ CD8 + T cells. Hierarchical clustering of enriched terms based on Jaccard’s similarity index (JC). (B and C) Gene-concept network plots depicting genes (blue dots) involved in enriched terms (red dots) associated with signaling events (B) and vascular interactions (C). (D) <t>Reactome</t> “cell surface interactions at the vascular cell wall” pathway associated genes upregulated or downregulated in lung ivs+ CD8 + T cells. For PEA an adj p value (FDR) ≤ 0.05 was used to determine significance. See also and .
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gene sets including kegg, go biological process reactome, and hallmark  (Broad Institute Inc)
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Pathway enrichment analysis (PEA) suggests ivs+ CD8 + T cells have an enhanced ability to interact with endothelial cells (A) Tree plot illustrating significantly enriched pathways in lung ivs+ CD8 + T cells. Hierarchical clustering of enriched terms based on Jaccard’s similarity index (JC). (B and C) Gene-concept network plots depicting genes (blue dots) involved in enriched terms (red dots) associated with signaling events (B) and vascular interactions (C). (D) <t>Reactome</t> “cell surface interactions at the vascular cell wall” pathway associated genes upregulated or downregulated in lung ivs+ CD8 + T cells. For PEA an adj p value (FDR) ≤ 0.05 was used to determine significance. See also and .
Gene Sets Including Kegg, Go Biological Process Reactome, And Hallmark, supplied by Broad Institute Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Pathway enrichment analysis (PEA) suggests ivs+ CD8 + T cells have an enhanced ability to interact with endothelial cells (A) Tree plot illustrating significantly enriched pathways in lung ivs+ CD8 + T cells. Hierarchical clustering of enriched terms based on Jaccard’s similarity index (JC). (B and C) Gene-concept network plots depicting genes (blue dots) involved in enriched terms (red dots) associated with signaling events (B) and vascular interactions (C). (D) Reactome “cell surface interactions at the vascular cell wall” pathway associated genes upregulated or downregulated in lung ivs+ CD8 + T cells. For PEA an adj p value (FDR) ≤ 0.05 was used to determine significance. See also and .

Journal: iScience

Article Title: Distinct transcriptomic signatures in pulmonary tissue resident and vascular resident-like T cells in nonhuman primates

doi: 10.1016/j.isci.2025.112745

Figure Lengend Snippet: Pathway enrichment analysis (PEA) suggests ivs+ CD8 + T cells have an enhanced ability to interact with endothelial cells (A) Tree plot illustrating significantly enriched pathways in lung ivs+ CD8 + T cells. Hierarchical clustering of enriched terms based on Jaccard’s similarity index (JC). (B and C) Gene-concept network plots depicting genes (blue dots) involved in enriched terms (red dots) associated with signaling events (B) and vascular interactions (C). (D) Reactome “cell surface interactions at the vascular cell wall” pathway associated genes upregulated or downregulated in lung ivs+ CD8 + T cells. For PEA an adj p value (FDR) ≤ 0.05 was used to determine significance. See also and .

Article Snippet: We performed PEA using the Reactome gene collection from The Broad Institute Molecular Signature Database (MSigDB), , which was filtered to contain only genes present in our dataset in order to avoid bias.

Techniques: